If you’ve been exploring anti-aging treatments in Malaysia, you’ve probably come across Profhilo—a trending injectable that promises smoother, firmer, more radiant skin without adding volume or altering your natural facial features. Often described as a “bio-remodeling” treatment rather than a filler
At GLOJAS Specialist Clinic, all Profhilo procedures are carried out by LCP-certified aesthetic doctors who adhere to strict medical standards and use only genuine IBSA-sourced products. With years of clinical experience and a strong reputation in Malaysia’s aesthetic field, the clinic ensures safe, ethical, and personalised treatments backed by evidence-based protocols.
Profhilo is an injectable hyaluronic acid (HA) treatment developed in Italy by IBSA, one of the most respected pharmaceutical companies in aesthetics. Unlike dermal fillers that add structure or lift, Profhilo focuses on improving skin quality from within by stimulating collagen and elastin production.
It became extremely popular in Malaysia for three key reasons:
Natural results – no overfilled or artificial look.
Minimal downtime – suitable for busy urban lifestyles.
High purity and safety – backed by clinical studies.
Profhilo contains one of the highest concentrations of ultra-pure hyaluronic acid available on the market (64 mg in 2 ml). Its key differentiator is IBSA’s patented NAHYCO® Hybrid Technology, which stabilizes HA without the use of chemical cross-linking agents. Here’s what happens after injection:
1. Slow-release hydration
Profhilo diffuses under the skin and hydrates tissue from within, acting like an internal moisturiser.
2. Collagen and elastin stimulation
Clinical studies show Profhilo triggers bio-remodelling, activating fibroblasts to rebuild collagen and elastin—essential proteins that improve firmness and elasticity.
3. Improved skin tone and structure
As the skin regenerates, patients experience: Smoother texture,
Brighter skin tone, Better elasticity and Reduced fine lines.
FDA-approved, non-surgical anti-aging treatment
Stimulates collagen and elastin for long-term skin repair (up to 12× increase)
Firms, tightens, and moderate skin laxity and sagging
100% pure Hyaluronic Acid for deep hydration and glow
Improves skin quality, skin texture, elasticity, and acne scarring
Clinically tested for safety and proven efficacy
Suitable for all skin types, ages, and skin tones
Delivers lasting results with minimal downtime
At licensed aesthetic clinics in Malaysia, the treatment is performed by MOH-registered aesthetic doctors or dermatologists trained in injection techniques.
Your doctor assesses:
Authenticity of Profhilo products is also verified—an important safety step in Malaysia’s aesthetic market.
The skin is cleansed, and topical numbing cream may be applied to enhance comfort.
Profhilo is injected using the Bio Aesthetic Points (BAP) method—5 injection points on each side of the face.
This ensures:
The entire session takes around 10–15 minutes.
Most patients return to daily activities immediately.
Timeframe | What to Expect |
Week 1 | Improved hydration, slight glow |
Week 3–4 | Stronger collagen activation, firmer skin |
After 2 sessions (1 month apart) | Peak results—smoother, lifted, radiant skin |
Longevity | 6–9 months depending on lifestyle & skin type |
While the original Profhilo is the most well-known, other HA bio-remodelling treatments exist. However, it’s important to note:
Authentic Profhilo products should always come with batch numbers and tamper-proof packaging—your clinic can show this during your visit.
To optimise healing and results:
These steps help protect the treated area and enhance the skin rejuvenation process.
Face
For overall radiance, hydration, and smoothing of fine lines.
Neck
Reduces neck creases, sagging, and skin thinning.
Hands
Rejuvenates aging hands with improved texture and hydration.
Body (Arms, Knees, Abdomen)
Improves crepey and lax skin in high-movement areas.
Feature | Profhilo | Fillers |
Purpose | Skin quality improvement | Volume restoration & contouring |
Result | Natural glow, firmness | Sharper features (chin, nose, jaw) |
Downtime | Minimal | Moderate (depending on area) |
Who it’s for | Those wanting subtle anti-aging | Those wanting structural changes |
Feature | Profhilo | Skin Boosters |
HA concentration | Higher | Lower |
Mechanism | Bio-remodelling | Hydration |
Frequency | Usually 2 sessions | 3–4 sessions |
Feature | Profhilo | Rejuran |
Main ingredient | Hyaluronic acid | Polynucleotides (PN) |
Effect | Hydration + elasticity | Repair + anti-inflammatory |
Best for | Overall glow & firmness | Acne scars & healing |
Many patients in Malaysia combine Profhilo with fillers, Rejuran, or lasers for comprehensive rejuvenation.
Profhilo is considered very safe due to its:
High purity
Absence of chemical crosslinking agents
CE-marked medical certification
Extensive clinical study history
Possible mild effects:
Temporary bumps
Mild redness
Slight tenderness
Small bruising
These typically resolve quickly.
Who should avoid Profhilo:
Pregnant or breastfeeding individuals
Those with active skin infections
Patients with severe allergies or autoimmune conditions (case-by-case assessment needed)
Always choose clinics with MOH-registered aesthetic practitioners to ensure safety and authenticity like GLOJAS Specialist Clinic, all treatments are conducted with strict safety protocols by MOH-registered aesthetic doctors who prioritise patient well-being.
Profhilo prices vary based on the clinic, doctor’s experience, and location.
Typical cost range:
RM1,800 – RM3,500 per syringe (2ml)
Most patients require:
2 sessions (1 month apart) for best results
Optional maintenance every 6–12 months
Factors influencing price:
Doctor’s qualification (GP vs aesthetic physician vs dermatologist)
Clinic location (KLCC, Bangsar, Mont Kiara are generally higher)
Product authenticity & brand certification
Package deals or combination treatments
Always confirm that your clinic uses authentic Profhilo from IBSA.
I tried a skin booster injection with Dr. Muya. After two sessions, my skin feels hydrated, smoother, and has a noticeable youthful glow.
This hyaluronic acid treatment smoothed my fine lines. Dr. Venu made the process comfortable and results look natural, firming my skin without adding volume.
Dr. Kiv explained everything before my bio-remodelling injection. Quick procedure, and my skin feels tighter and rejuvenated without appearing artificial.
I had a skin hydration booster to improve texture. Dr. Muya targeted key areas, and my skin now looks subtly lifted and more radiant.
My skin felt loose. Dr. Venu used a bio-remodelling injection, and within weeks, I noticed improved firmness and smoother fine lines.
I avoided fillers and tried a hydration booster. Dr. Kiv ensured comfort, and now my skin looks plump, refreshed, and naturally luminous.
This skin booster treatment improved hydration and elasticity. Dr. Muya guided the process expertly, giving noticeable natural rejuvenation without downtime.
Dr. Venu treated my face with a hyaluronic acid injection. Subtle but effective, especially around eyes and mouth, improving firmness and skin texture.
After two skin booster sessions, my skin texture improved significantly. Dr. Kiv was precise and informative, giving a smooth, youthful finish.
This anti-aging injection firmed my skin naturally. Dr. Muya ensured a painless process, and results were noticeable with minimal downtime.
Authentic Product
We use only certified, original skin boosters from authorized medical distributors, ensuring consistent quality, safety, and clinical efficacy for all patients.
Safe Injection Technique
Treatments are delivered using medically approved, minimally painful injection methods, prioritizing patient safety and comfort while maintaining precise, controlled administration.
Advanced BAP Injection Points
Our doctors target specific Bio Aesthetic Points (BAP) to maximize hydration, firmness, and natural skin tightening, optimizing outcomes with minimal downtime.
Personalized Treatment Planning
Each treatment plan is tailored to individual skin condition, age, and concerns, ensuring effective, natural-looking, and evidence-based results.
Doctor-Supervised Procedures
All injections and assessments are performed and directly supervised by MOH-registered, LCP-certified aesthetic physicians, guaranteeing the highest standard of clinical care.
Expertise in Bio-Remodelling Treatments
We specialize in advanced skin boosters and collagen-stimulating injectables, delivering long-lasting, natural rejuvenation backed by clinical experience and peer-reviewed evidence.
At GLOJAS Specialist Clinic, MOH-registered, LCP-certified aesthetic doctors deliver an advanced skin treatments using proven medical technology, ensuring safe, effective results while prioritizing patient safety, satisfaction, and long-lasting skin health.
Dr. Siti Muyassarah Rusli is a board-certified plastic surgeon and LCP-certified aesthetic physician at GLOJAS, Malaysia. With global fellowships in reconstructive and aesthetic surgery, she specializes in non-surgical facial enhancements, body contouring, and skin rejuvenation, delivering evidence-based, patient-centric, and natural-looking results.