If you’ve been scrolling through social media or chatting with friends about skincare in KL, you’ve likely heard two names on repeat: Profhilo and Rejuran. These aren’t your average facials; they are heavy hitters in the world of medical aesthetics.
But with all the buzz, it’s easy to get confused. Is one a filler? Does the other really involve salmon? In this guide, we’re breaking down the Profhilo vs Rejuran debate specifically for the Malaysian context, helping you decide which “glow-up” is worth your ringgit.
Understanding Skin Boosters in Malaysia
In Malaysia’s humid climate, our skin faces unique challenges—from “maskne” and air-con dehydration to premature aging caused by intense UV exposure. Skin boosters have become the go-to solution for those who want more than what a bottle of serum can provide.
What Are Injectable Skin Boosters?
Unlike traditional dermal fillers that “fill” a specific wrinkle or add volume to your cheeks, skin boosters are designed to improve the overall quality of your skin. Think of them as internal moisturizers or biological “re-modelers” that work from the inside out to enhance texture, tone, and elasticity.
Why Profhilo and Rejuran Are Popular in Malaysian Clinics
Both treatments have surged in popularity across clinics in the Klang Valley and beyond because they offer minimal downtime and natural-looking results. Malaysians generally prefer the “glass skin” look over a frozen or overfilled appearance, making these “injectable skincare” options a perfect fit.
Suitable Skin Types and Concerns for Malaysian Skin
Profhilo: Perfect for those with dry, “tired” skin or early sagging.
Rejuran: A savior for those with acne scars, large pores, or sensitive, inflamed skin.
What Is Profhilo?
How Profhilo Works (Hybrid Hyaluronic Acid Technology)
Profhilo is often called “the 5-point face lift,” but it’s technically a bio-remodeling treatment. It uses a patented hybrid technology combining both high and low molecular weight Hyaluronic Acid (HA). Instead of staying in one spot, it spreads like a “honey-like” gel under your skin to kickstart collagen and elastin production.
Key Benefits of Profhilo for Skin Hydration and Firmness
Intense Hydration: Holds 1,000 times its weight in water.
Bio-Remodeling: Not just a moisturizer, it actually firms up the skin “scaffold.”
The Glow: Delivers that sought-after “lit-from-within” radiance.
Ideal Candidates for Profhilo in Malaysia
If you’re in your 30s or 40s and noticing your skin looks a bit “crepey” or dehydrated from constant air-conditioning, Profhilo is likely your best match.
What Is Rejuran?
How Rejuran Works (PN / Salmon DNA Technology)
Rejuran Healer is a Korean innovation that uses Polynucleotides (PN)—DNA fragments derived from salmon. It sounds a bit “fishy,” but salmon DNA is highly compatible with human skin. According to clinical data, PN helps repair damaged skin cells and reduces inflammation.
Key Benefits of Rejuran for Skin Repair and Texture
Healing Power: Excellent for repairing the skin barrier.
Scar Revision: Proven to help flatten depressed acne scars.
Pore Tightening: Regulates oil production and shrinks enlarged pores.
Ideal Candidates for Rejuran in Malaysia
Perfect for younger patients dealing with post-acne scarring or anyone with sensitive skin that reacts easily to the tropical heat and pollution.
Profhilo vs Rejuran: Key Differences
| Feature | Profhilo | Rejuran Healer |
| Main Ingredient | Pure Hyaluronic Acid (HA) | Polynucleotides (PN) |
| Primary Goal | Hydration & Firming | Repair & Regeneration |
| Injection Points | 10 points (5 per side) | Multiple micro-injections |
| Downtime | Minimal (24 hours) | Small “bumps” (24–72 hours) |
| Best For | Dull, sagging, dry skin | Scars, pores, sensitivity |
Ingredient and Technology Comparison
While Profhilo relies on high-concentration HA for structural support, Rejuran uses DNA building blocks to tell your cells to “fix” themselves.
Treatment Goals: Hydration vs Skin Repair
If your skin is thirsty, go Profhilo. If your skin is damaged, go Rejuran.
Results Timeline and Longevity
Profhilo: You’ll see a “glow” within a week, with full results after the 2nd session. Lasts ~6 months.
Rejuran: Results are gradual as the skin heals. Best seen after 3–4 sessions. Lasts ~6–9 months.
Profhilo vs Rejuran Results on Malaysian Skin
Effectiveness for Acne Scars and Enlarged Pores
In the battle for texture, Rejuran wins. Its ability to regenerate tissue makes it the gold standard for smoothing out the “pitting” left behind by adult acne, a common concern in Malaysia.
Anti-Aging Benefits for Humid Climate Conditions
The heavy humidity in Malaysia often makes thick creams feel greasy. Profhilo provides that deep hydration without the need for heavy topical products, making it an ideal anti-aging tool for the local climate.
Cost Comparison in Malaysia
Average Profhilo Treatment Price in Malaysia
Expect to pay between RM 2,000 to RM 2,800 per syringe. Usually, 2 sessions are required for the initial phase.
Average Rejuran Treatment Price in Malaysia
Rejuran typically ranges from RM 1,200 to RM 2,000 per syringe. Since you usually need 3 sessions, the total investment is comparable to Profhilo.
Factors That Affect Pricing Across Clinics
Prices vary based on the doctor’s experience, clinic location (Bangsar vs. Subang), and whether they are using authentic products verified by the Ministry of Health (MOH).
Safety, Approval, and Medical Considerations
MOH Malaysia and International Regulatory Status
Both treatments are approved for use in Malaysia. Always ensure your clinic is registered with the National Pharmaceutical Regulatory Agency (NPRA) to avoid counterfeit “bootleg” injectables.
Is Profhilo or Rejuran Halal-Friendly?
This is a common question. While the HA in Profhilo is synthetic/bio-fermented (non-animal), Rejuran is derived from salmon DNA. Most scholars consider topical or medicinal use of fish-derived ingredients permissible, but always check with your local aesthetician if you have specific concerns.
Choosing Between Profhilo and Rejuran in Malaysia
Which Treatment Is Better for Your Skin Concern?
Choose Profhilo if: You want a “lifting” effect and intense moisture.
Choose Rejuran if: You want to fix “holes” (scars) and redness.
Can Profhilo and Rejuran Be Combined?
Absolutely! Many Malaysian doctors recommend a combination protocol—using Rejuran to repair the skin’s foundation and Profhilo to add the “finishing touch” of hydration and glow.
Frequently Asked Questions
How Long Do Results Last in Malaysian Climate?
Generally 6 to 9 months. However, high sun exposure without SPF can degrade HA faster, so don’t skip the sunscreen!
Which Is Better for First-Time Aesthetic Patients?
Profhilo is often preferred by beginners because it involves fewer injection points (less “stinging”) and has almost zero downtime.
Final Verdict: Profhilo or Rejuran — Which Should You Choose in Malaysia?
There is no “better” treatment—only the one that fits your skin’s current story. If you’re looking for an immediate wedding-ready glow and firmness, Profhilo is your best friend. If you’re playing the long game to heal years of acne damage and sensitivity, Rejuran is the MVP.