Profhilo vs Dermal Fillers: Which Treatment Works Best?

Understanding Profhilo vs Dermal Fillers

The main difference between Profhilo vs dermal fillers lies in their purpose: Profhilo boosts overall skin quality by hydrating and stimulating collagen, while dermal fillers add shape, volume, and structure. Profhilo spreads evenly to refresh the skin, while fillers target specific areas to enhance facial contours. Both are popular among adults for different reasons, but they serve very different goals.

Introduction: The Rise of Profhilo vs Dermal Fillers

In recent years, aesthetic medicine has evolved beyond traditional beauty treatments. Adults today seek subtle, natural-looking enhancements that improve skin quality rather than drastically changing facial structure.

This is where Profhilo and dermal fillers stand out—each offering unique benefits, technologies, and expected outcomes. While both involve hyaluronic acid, understanding their differences helps adults choose the right approach based on goals, skin needs, and treatment expectations.

This article breaks down Profhilo vs dermal fillers in a clear, humanized way—covering how each works, key differences, safety profiles, ideal candidates (adults), and frequently asked questions.

What Is Profhilo?

Profhilo is an injectable skin bio-remodelling product containing one of the highest concentrations of pure hyaluronic acid (HA). Designed to improve skin quality, it:

• deeply hydrates
• increases elasticity
• improves firmness
• stimulates collagen and elastin
• reduces crepey texture

Unlike fillers, Profhilo does not add volume or change facial contours.

Key Characteristics:

• Ultrapure hyaluronic acid
• No BDDE chemical cross-linkers
• Flows freely under the skin
• Offers whole-face rejuvenation instead of targeted shaping

What Are Dermal Fillers?

Dermal fillers are injectable gels used to restore volume, enhance facial contours, and reduce static lines. They are commonly used for:

• lip shaping
• cheek augmentation
• jawline contouring
• chin projection
• deep wrinkle correction

Most fillers are made from cross-linked hyaluronic acid, giving them a thicker consistency that stays in place after injection.

Key Characteristics:

• Add structure and volume
• Restore lost facial definition
• Useful for sculpting and reshaping
• Different densities for different areas

Profhilo vs Dermal Fillers: The Core Differences

While both contain hyaluronic acid, they work very differently.

Side-by-Side Comparison Table

How Does Profhilo Work?

Profhilo uses Hybrid Cooperative Complexes (HCC) created using patented NAHYCO® technology. This creates a stabilised HA formulation without chemical cross-linkers.

How it acts in the skin:

1. Hydrates deep tissues
2. Spreads evenly for uniform improvement
3. Stimulates fibroblasts to produce collagen & elastin
4. Improves tissue quality over several weeks

It behaves like a supercharged internal moisturizer, not a sculpting product.

How Do Dermal Fillers Work?

Fillers use cross-linked hyaluronic acid to create a gel that maintains shape.

How it acts in the skin:

1. Adds volume immediately
2. Fills folds or depressions
3. Supports facial structure
4. Enhances key features like lips, jawline, and cheeks

Fillers hold their form and stay exactly where the injector places them.

Profhilo vs Dermal Fillers: Areas Commonly Treated

Profhilo

Adults commonly use it for:

• Face
• Neck
• Hands
• Décolletage
• Arms

Best for crepey, dehydrated, or aging skin.

Dermal Fillers

Commonly used for structural enhancement in adults:

• Cheeks
• Chin
• Jawline
• Under-eyes (tear troughs)
• Lips
• Nasolabial folds
• Marionette lines

Benefits of Profhilo

Profhilo is known for its deep hydration and ability to rejuvenate the skin from within. Its unique formulation spreads evenly under the skin, giving a naturally refreshed look. Key benefits include:

• Restores hydration: Replenishes moisture levels for healthier, dewy skin.

• Increases skin elasticity: Helps the skin feel firmer and more resilient.

• Gives a natural glow: Enhances radiance without adding volume.

• Smoothens fine creases: Softens small lines, especially around the cheeks and under-eye area.

• Improves overall skin quality: Boosts texture, tone, and smoothness over time.

• Lightweight and natural: Feels subtle and integrates seamlessly into the skin.

Benefits of Dermal Fillers

Dermal fillers are ideal for sculpting, lifting, and enhancing facial features. They focus on restoring structure and adding definition where needed. Key benefits include:

• Restores volume loss: Adds back fullness in areas that have become hollow.

• Defines facial features: Shapes the nose, chin, cheeks, and more for improved contour.

• Contours jawline & chin: Creates sharper, more balanced facial proportions.

• Lifts sagging areas: Supports tissues to give a more youthful appearance.

• Smooths deep wrinkles: Helps reduce the appearance of pronounced folds.

• Adds plumpness (e.g., lips): Enhances natural volume for a fuller look.

Profhilo vs Dermal Fillers: Which One Should Adults Choose?

Choose Profhilo if the goal is:

Profhilo is a skin‑booster and bio‑remodeller, ideal for adults who want natural rejuvenation rather than adding volume.

• Better skin hydration: Deeply moisturizes and restores a healthy glow to dry or dull skin.

• Improved elasticity: Helps the skin regain firmness and resilience, making it feel softer and more supple.

• Subtle, natural radiance: Provides a “lit‑from‑within” glow without altering your facial structure.

• Tissue tightening: Gently firms sagging areas, improving skin tone over time.

• “Glass skin” effect: Creates smooth, luminous, and even-textured skin for that dewy, youthful look.

• Treating crepey areas: Ideal for fine lines and loose skin on the neck, décolletage, or hands.

Best for: Those who want overall skin improvement, a refreshed look, and natural, subtle changes rather than dramatic volume.

Choose Dermal Fillers if the goal is:

Dermal fillers are volumizing and contouring treatments, perfect for adults looking to reshape or lift their facial features.

• Adding shape and structure: Restores volume lost due to aging or weight changes.

• Enhancing facial balance: Improves harmony between features like cheeks, chin, and jawline.

• Boosting symmetry: Corrects minor asymmetries for a more balanced appearance.

• Lifting sagging areas: Provides support to drooping cheeks, jowls, or brows.

• Creating sharper contours: Sculpted cheekbones, jawline, and chin for a more defined look.

Best for: Those seeking visible changes in facial structure, defined contours, or restoration of lost volume.

Profhilo vs Dermal Fillers: Treatment Experience

Here’s a general awareness outline of how both procedures differ. This is not a step-by-step instruction, only conceptual understanding.

Profhilo

• Applies the 5 Bio-Aesthetic Points (BAP)
• Minimal injection points
• Mild bumps that settle quickly

Fillers

• Strategic placement based on facial anatomy
• Requires shaping and sculpting
• May involve different techniques like linear threading or bolus injections

Profhilo vs Dermal Fillers: How Long Do Results Last?

Profhilo

• Duration of results: Typically lasts 6–9 months.

• Treatment schedule: Most patients undergo two sessions, spaced about 4 weeks apart, for optimal results.

• Maintenance: After the initial sessions, a single “top-up” session once or twice a year can help maintain hydration, firmness, and glow.

• Effect: Profhilo focuses on hydration and skin quality, so the changes are subtle, gradual, and natural-looking rather than volumizing.

Dermal Fillers

• Duration of results: Varies between 6–18 months, depending on filler type, density, and the area treated.

  • Thicker fillers for cheeks or jawline may last longer (up to 18 months).

  • Softer fillers for lips or fine lines may last around 6–12 months.

• Effect: Dermal fillers provide instant volume and contour, making them ideal for lifting, shaping, or adding plumpness to specific facial areas.

• Maintenance: Touch-ups are needed as the filler gradually absorbs, ensuring the desired shape and volume are maintained over time.

Profhilo vs Dermal Fillers: Safety Considerations

Profhilo

• Highly biocompatible
• Minimal risk of reactions
• No chemical cross-linkers

Dermal Fillers

• Generally safe when administered by trained professionals
• May cause temporary swelling, redness, or bruising
• Rare complications include vascular issues (handled medically by professionals)

Profhilo vs Dermal Fillers: Cost Differences 

Profhilo

• Typical cost: about RM 2,500 – RM 3,500 per syringe/vial.

• Some clinics list a lower “trial” price (e.g. ~RM 1,699) for first-time customers. 

• Because patients often need two sessions (spaced ~4 weeks apart) for best results, the full treatment can cost around RM 5,000–RM 7,000 (before any maintenance). 

• On a maintenance basis (once or twice a year), expect additional costs as advised by your clinic.

Dermal Fillers

• In 2025, dermal filler prices in Malaysia generally range from RM 1,200 – RM 3,500 per syringe (1 ml). 

• Typical price for common treatments (depending on area):

  • Lips: RM 1,200 – RM 1,800 per syringe 

  • Cheeks: RM 1,500 – RM 2,500 per syringe 

  • Chin / Jawline: RM 1,800 – RM 3,000 per syringe 

  • Nasolabial folds, under‑eyes, etc: generally within RM 1,000 – RM 2,000 per syringe depending on depth and brand. 

• For larger treatment zones (e.g. sculpting cheeks + jaw + chin), the overall cost can add up — some clinics quote RM 4,000 – RM 8,000 for multi‑syringe “full‑face” packages.

10 FAQs About Profhilo vs Dermal Fillers

1. Is Profhilo a type of filler?

No. Profhilo does not add volume or shape; it improves skin quality and hydration.

2. Can you combine Profhilo with dermal fillers?

Yes—many adults combine both for comprehensive rejuvenation (hydration + structure).

3. Which one gives more dramatic results?

Fillers offer more noticeable, structural changes. Profhilo gives subtle, natural improvement.

4. Does Profhilo help with sagging skin?

It can mildly tighten the skin by stimulating collagen and elastin.

5. Do fillers look natural?

When done by experienced professionals, fillers can look very natural and balanced.

6. Which treatment is better for fine lines?

Profhilo is often preferred for superficial fine lines caused by dryness or loss of elasticity.

7. Which treatment lasts longer?

Some fillers last longer than Profhilo, depending on density and placement.

8. Can Profhilo replace fillers?

Not necessarily—they serve different purposes. Profhilo improves skin; fillers sculpt and shape.

9. Are both treatments safe?

Yes, when performed by licensed and trained aesthetic practitioners.

10. Which is better for the neck?

Profhilo is often preferred for overall neck quality, while fillers may be used for deeper lines in adults.

Conclusion

Understanding Profhilo vs dermal fillers helps adults make informed choices based on their goals. Profhilo focuses on hydration, elasticity, and skin health, while fillers work to add structure, lift, and contour. Many adults use both as part of a layered aesthetic plan—improving skin quality with Profhilo and enhancing facial shape with fillers.

Both treatments have distinct roles and complement each other when used under professional guidance.