In the evolving world of aesthetic medicine, this specialized formula has emerged as a revolutionary “biostimulator.” Unlike traditional treatments that simply mask aging, this Plenhyage injectable skin booster focuses on cellular repair and long-term skin health.
What Is Plenhyage Skin Booster?

Overview of Plenhyage Polynucleotide Treatment
This is an injectable treatment derived from Polynucleotides (PN). These are DNA fractions extracted from natural sources (usually salmon DNA) that are highly purified. When administered, these molecules act as messengers to trigger deep tissue repair.
How the PN Skin Booster Works on the Skin
The treatment works by stimulating fibroblasts, the cells responsible for producing collagen and elastin. Instead of just adding temporary moisture, it “wakes up” your skin cells, encouraging them to heal damage caused by UV rays, pollution, and aging.
Key Ingredients (PN-HPT® Technology)
The secret lies in PN-HPT® (Polynucleotide High Purification Technology). This patented process ensures the molecules are bio-compatible and highly effective at promoting tissue regeneration without causing significant inflammation.
Benefits of the Treatment
Skin Regeneration and Repair
This therapy is excellent for healing scarred or damaged tissue. It promotes a healthier skin barrier and accelerates the recovery of the dermis, making it a premier aesthetic treatment for those seeking long-term quality.
Improved Skin Elasticity and Firmness
By boosting elastin production, the skin becomes more resilient. You will notice a visible “snap-back” quality in treated areas, reducing sagging—one of the core benefits of this polynucleotide booster.
Deep Hydration and Skin Revitalization
Polynucleotides have a natural ability to bind water. This provides a deep, internal hydration that topical creams simply cannot reach, resulting in total skin rejuvenation.
Anti-Aging Effects
This anti-aging treatment effectively targets fine lines and wrinkles. Because it works at a cellular level, the results look completely natural—never “overfilled.”
Care for Dull, Tired, or Damaged Skin
If your complexion looks fatigued, the formula improves microcirculation and oxygenation, restoring a youthful radiance and vastly improving overall skin quality.
What Areas Can Be Treated?
Face Rejuvenation
The product is widely used across the cheeks, forehead, and jawline to improve overall texture and tone.
Under Eyes
The under eye treatment is one of its most popular uses. It is a game-changer for dark circles and “crepey” skin where fillers might look too heavy.
Neck and Décolletage
Applying the booster to the neck and décolletage strengthens thin skin, reducing “necklace lines” and sun damage.
Hands
It can rejuvenate sun-damaged skin on the hands by thickening the dermis and making veins and tendons less prominent.
Body Skin Quality Improvement
Various treatment areas include the stomach, inner arms, or knees to treat stretch marks and sagging.
The Treatment Process
Pre-Treatment Consultation
Your practitioner will examine your skin and medical history to ensure the Plenhyage procedure is the right choice for your specific concerns.
How the Injections are Administered
During the session, the formula is administered using very fine needles or a cannula. The technique varies depending on the area, often using a “bumping” technique.
Duration and Comfort Level
The procedure typically takes 30 to 45 minutes. A topical numbing cream is usually applied beforehand to ensure the experience is comfortable.
Post-Treatment Care and Recovery
Recovery time is minimal. You can return to most activities immediately, as there is very little downtime associated with the injections.
Expected Results
When Will You See Results?
Initial hydration may be visible within a week, but the results timeline shows the real magic at 3 to 4 weeks as new collagen forms.
Short-Term vs Long-Term Skin Improvements
Initially, you’ll see a “glow.” Long-term, you will notice structural changes: thicker skin, fewer lines, and better contour.
How Long Do the Effects Last?
Results typically last between 6 to 9 months, depending on your lifestyle and skin type.
Before and After Expectations
Viewing before and after photos reveals pores look smaller, redness is reduced, and the skin feels significantly firmer to the touch.
How Many Sessions Are Needed?
Recommended Treatment Protocol
For optimal results, a course of 2 to 4 sessions, spaced about 3 weeks apart, is usually recommended.
Maintenance Treatments Explained
To maintain the regenerative benefits, a single maintenance treatment every 6 months is ideal.
Can it be Combined with Other Aesthetic Treatments?
Yes! It works beautifully alongside Microneedling or Dermal Fillers to provide a comprehensive rejuvenation.
Comparisons
Plenhyage vs Profhilo
When comparing these two, Profhilo is Hyaluronic Acid-based for hydration, while the polynucleotide option focuses on DNA-level repair.
Plenhyage vs Hyaluronic Acid Skin Boosters
In the debate of PN vs HA skin boosters, polynucleotides offer more long-term structural repair. It is often superior for thin, damaged skin.
Safety and Side Effects
Common Side Effects
Mild swelling or redness are common side effects. These usually resolve within 24 to 48 hours.
Is it Safe?
Yes, it is CE-marked with a high safety profile. Risks are extremely low due to its bio-compatible nature.
Cost of Treatment
Average Cost per Session
In Malaysia, Plenhyage skin booster treatment typically costs RM1,000 to over RM2,000 per session. Prices vary based on the practitioner’s expertise and the number of syringes required.
People Also Asked (PAA) FAQs
Is Plenhyage the same as Profhilo? No, they use different active ingredients (Polynucleotides vs HA).
Does it add volume? No, it improves skin quality and thickness, not facial volume.
How painful is it? It is a well-tolerated treatment with topical numbing.
Book Your Plenhyage Treatment at GLOJAS Specialist Clinic
If you are looking for a skin booster near me, ensure you choose a reputable Plenhyage clinic. For those seeking treatment in Malaysia or specifically a skin booster in KL, many top-tier aesthetic centers now offer this advanced polynucleotide therapy.
GLOJAS Specialist Clinic offers expert Plenhyage skin booster treatments in Malaysia, utilizing advanced polynucleotide technology to deliver superior skin regeneration and long-lasting facial rejuvenation for all patients.