Looking for the right Rejuran injection for your skin? Rejuran isn’t one-size-fits-all. The Korean PDRN/PN skin booster comes in 3 main clinical formulas — Healer, I, and S — each designed for different skin layers, concerns, and injection depths. Here’s how to choose.
What Is Rejuran: PDRN Skin Healer Explained
Rejuran is a polynucleotide (PN) skin booster derived from purified salmon DNA fragments. Unlike hyaluronic acid fillers that add volume, Rejuran works at the cellular level to repair damaged skin, stimulate collagen production, and improve overall skin health. It’s often called a “skin healer” because PN has wound-healing and anti-inflammatory properties that support natural regeneration.
Core benefits of all Rejuran formulas:
- Stimulates collagen + elastin production
- Improves skin elasticity, hydration, and texture
- Repairs skin barrier and accelerates cell turnover
- Biocompatible with human skin, minimal allergy risk
Rejuran Healer: Best For Full Face Rejuvenation
Also called: Rejuran H, Black label
Best for: Overall anti-aging, dull skin, enlarged pores, fine lines, skin texture
How it works: Medium-viscosity PN formula injected into the dermis of the whole face. It restores skin health by rebuilding the epidermis and dermis, increasing elasticity.
Target area: Full face, neck, hands
Depth: Mid to superficial dermis
Key concerns: Aging skin, sagging, enlarged pores, mild acne scars, dehydration
Rejuran I: Best For Under Eye & Delicate Areas
Also called: Rejuran Eye, White label
Best for: Dark eye circles, crow’s feet, crepey under-eye skin, thin eyelid skin
How it works: Thinnest, lowest-viscosity formula designed for the fragile periorbital area where skin is only 0.5mm thick. Safely thickens dermis without causing lumps.
Target area: Under-eye, crow’s feet, eyelids
Depth: Superficial dermis
Key concerns: Dark circles, fine wrinkles, skin laxity around eyes
Rejuran S: Best For Acne Scars & Depressed Scars
Also called: Rejuran Scar, Blue label
Best for: Ice-pick, boxcar, and rolling acne scars; depressed scars; stretch marks
How it works: Highest viscosity, thickest formula. It provides structural support to lift depressed scars while PN repairs scar tissue from within.
Target area: Localized scar areas on face or body
Depth: Deep dermis to subdermal layer
Key concerns: Atrophic acne scars, pitted scars, tissue restoration
Rejuran Healer vs Rejuran I vs Rejuran S: Key Differences
The 3 formulas use the same PN technology but differ in viscosity, concentration, and indication. Picking the wrong one means poor results or unnecessary swelling.
1. Viscosity & Flow
- Rejuran S = Thickest, for deep structural filling
- Rejuran Healer = Medium, spreads evenly across face
- Rejuran I = Thinnest, for delicate thin skin
2. Treatment Goal
- Healer: General rejuvenation + prevention
- I: Targeted eye area repair
- S: Scar remodeling + volume in dents
3. Pain & Bumps
Thicker formulas = more post-injection bumps. S has the longest bump duration, while I settles fastest due to thin consistency.
Rejuran Formula Comparison Table: Area, Depth, Concentration
Formula | Color Label | Viscosity | Best Area | Injection Depth | Key Indication |
|---|---|---|---|---|---|
Rejuran Healer | Black | Medium | Full face, neck | Mid dermis | Aging, pores, texture |
Rejuran I | White | Thin/Low | Under-eye, crow’s feet | Superficial dermis | Dark circles, fine lines |
Rejuran S | Blue | High/Thick | Depressed acne scars | Deep dermis | Acne scars, tissue repair |
Rejuran HB | Red | Medium + Lidocaine | Full face | Mid dermis | Hydration + less pain |
Which Rejuran Is Best For Your Skin Concern
Skin Concern | Recommended Formula | Why |
|---|---|---|
Dull, aging skin | Rejuran Healer | Whole-face collagen boost |
Large pores | Rejuran Healer | Tightens skin + regulates sebum |
Dark eye circles | Rejuran I | Thin enough for under-eye, reduces crepey skin |
Boxcar/ice-pick scars | Rejuran S | High viscosity lifts depressed scars |
Sensitive, damaged skin | Rejuran Healer | Repairs skin barrier |
Preventive anti-aging 25+ | Rejuran Healer | Maintenance of skin quality |
Note: LCP-certified doctors often combine formulas in one session — e.g. Healer for face + I for eyes.
Rejuran Price in Malaysia 2026: Healer vs I vs S
Prices vary by clinic location, doctor experience, and whether it’s authentic MDA-approved Rejuran. Based on 2025–2026 KL/PJ market rates:
Formula | Price Per Session Malaysia | 3-Session Package |
|---|---|---|
Rejuran Healer | RM1,200 – RM2,500 | From RM4,200 |
Rejuran I | RM600 – RM1,200 | Varies by clinic |
Rejuran S | RM900 – RM1,800 | Varies by clinic |
Rejuran HB | RM1,000 – RM1,800 | Varies by clinic |
Factors affecting cost: Type used — S or HB may cost more than Healer, clinic location, doctor’s skill, and genuine product. Trial prices can start from RM1,699.
How Many Rejuran Sessions Needed For Each Formula
Standard protocol for all 3 formulas:
- Initial cycle: 3 to 4 sessions, spaced 4 weeks apart
- Maintenance: Every 6 to 12 months
- Visible results: Initial hydration at 1 week, collagen regeneration at 2-4 weeks, best results 1-3 months after completing full cycle
Why 3 sessions? PN stimulates gradual cell repair. One session gives glow, but 3-4 sessions rebuild skin structure for results lasting 6-12 months.
Rejuran Side Effects & Downtime By Formula
Rejuran is very safe due to DNA biocompatibility. Side effects are temporary and technique-dependent.
Common to all: Small mosquito-bite bumps, mild redness, occasional bruising at injection sites. Bumps typically resolve in 24-48 hours.
Formula | Typical Downtime | Notes |
|---|---|---|
Rejuran I | 1-2 days | Thinnest — bumps settle fastest |
Rejuran Healer | 1-3 days | Medium viscosity — lumpy feeling goes away in 30–60 min |
Rejuran S | 2-5 days | Thickest — bumps/bruising last longer. Bruising, if it occurs, fades in 1-2 weeks |
Pain level: Treatment is quite tolerable. Numbing cream is applied before injection. Rejuran HB contains lidocaine for less pain.
Safety: Serious adverse effects are rare when done by LCP-certified doctors. Always choose MOH-licensed clinics with authentic MDA-approved Rejuran.
5 FAQs
1. Can I combine Rejuran Healer and Rejuran I in one session?
Yes. Doctors commonly use Rejuran Healer for the full face and Rejuran I for the under-eye in the same appointment because the eye area needs a thinner formula. Your doctor will recommend the right variant based on your skin concerns.
2. Is Rejuran S painful compared to Rejuran Healer?
Rejuran S is thicker, so injection feels more “dense,” but all formulas use numbing cream before treatment. Pain is subjective, but Healer and S have similar tolerability. If you’re concerned, ask for Rejuran HB, which includes lidocaine.
3. How long does Rejuran I last for dark eye circles?
Like other formulas, Rejuran I results typically last 6 to 12 months. You’ll need 3-4 initial sessions 4 weeks apart, then maintenance every 6-12 months. Improvement in dark circles is gradual as collagen rebuilds.
4. Which Rejuran is best for large pores?
Rejuran Healer is the gold standard for large pores. It stimulates collagen to tighten skin, reduces sebum, and improves texture. It’s injected across the full face where pores are most visible.
5. How much does Rejuran S cost in Malaysia?
In 2026, Rejuran S costs RM900 – RM1,800 per session in Malaysia. S or HB might cost a bit more than Healer due to formulation. Most clinics recommend 3 sessions for scar remodeling.
Bottom line: Think of it like skincare serums — Healer = daily moisturizer for all, I = eye cream for delicate zones, S = spot treatment for scars. See an LCP-certified aesthetic doctor for a proper skin assessment before deciding.